Milurit contains allopurinol, a compound that inhibits the enzyme xanthine oxidase. This enzyme is responsible for converting purines (naturally occurring substances in food and the body) into uric acid. By blocking this process, Milurit lowers the concentration of uric acid in the blood and urine, reducing the risk of urate crystal formation in joints or kidneys.
When Is Milurit Prescribed?
1. Gout (Podagra)
Gout is a painful inflammatory condition caused by uric acid crystals accumulating in the joints—typically the big toe, ankles, or knees. Milurit is not used during acute gout attacks but is prescribed afterward to prevent recurrences.
2. Kidney Stones
In patients with uric acid kidney stones, Milurit helps by reducing the amount of uric acid in urine, making stone formation less likely.
3. Chemotherapy or Radiation Therapy
Cancer treatments can lead to rapid cell breakdown, releasing purines into the blood and increasing uric acid levels. Milurit is used to prevent tumor lysis syndrome in such cases.
4. Chronic Hyperuricemia
Some people naturally produce more uric acid or excrete less of it. Milurit helps manage long-term elevated uric acid even without acute symptoms.
How Is Milurit Taken?
-
Usually prescribed in tablet form.
-
Initial dosage is low and gradually increased to reduce the risk of side effects.
-
Often taken once daily, after meals, with plenty of fluids to support kidney function.
-
Dosage depends on uric acid levels, kidney function, and the underlying condition.
Important Considerations
1. Not for Acute Attacks
Milurit should not be started during an active gout attack, as it may initially worsen symptoms. Treatment typically begins after inflammation subsides.
2. Regular Monitoring Needed
Uric acid levels and kidney function should be checked periodically. Adjustments may be necessary over time.
3. Drug Interactions
Milurit may interact with:
-
Azathioprine or mercaptopurine (used in immunosuppression)
-
Certain antibiotics
-
Anticoagulants like warfarin
Always inform your doctor about other medications you’re taking.
4. Side Effects
Most people tolerate Milurit well, but potential side effects include:
-
Skin rash or allergic reaction
-
Gastrointestinal discomfort
-
Liver enzyme elevation (rare)
Any serious symptoms, like persistent rash or fever, require immediate medical attention.
Lifestyle Tips Alongside Milurit
To enhance Milurit’s effectiveness and prevent new uric acid buildup:
-
Stay hydrated: Drink plenty of water
-
Limit alcohol, especially beer and spirits
-
Reduce intake of purine-rich foods: organ meats, red meat, shellfish
-
Maintain a healthy weight
-
Avoid sugary drinks and excess fructose
Conclusion
Milurit is a long-term solution for managing excess uric acid in the body. Whether you’re dealing with recurrent gout, uric acid stones, or elevated levels due to other health conditions, Milurit helps reduce complications and improve quality of life. As always, proper medical supervision and consistent monitoring are essential for safe and effective use.
Source: insightmagazin.hu – Milurit: mire jó és mikor alkalmazzák?